Ефективність засобу «Тінідафен» за давенеозу курей та його вплив на гематологічні показники

Abstract

У статті наведені результати досліджень ефективності антигельмінтних препаратів за спонтанного давенеозу курей та їх вплив на гематологічні показники. Встановлено, що на 21 добу досліду екстенсефективність засобу «Тінідафен» та фенбендазолу склала 100 %, Застосування засобу «Тінідафен» вже на 14 добу призвело до нормалізації гематологічних показників і суттєвого зменшення лейкоцитарного індексу інтоксикації. При застосуванні фенбендазолу гематологічні показники наблизились до норми на 21 добу досліду на що вказує низький рівень лейкоцитарного індексу інтоксикації ‒ 0,261 ОД.

For spontaneous hemorrhagic hens, the efficacy of the complex drug «Tinidafen» and fenbendazole at 3 days was 25%. For 7 days in the first experimental group (Tinidafen - 0.25 g / kg body weight), the extensiveness was 33.3%, in the second group (Tinadaphen - 0.5 g / kg body weight) - 91.6%, and in the third (fenbendazole 0.1 g / kg body weight) - 83.3%. For 14 days in the IE group, the EE index was 50%, while in the 2nd and 3rd groups 91.6%. Extensive efficacy of “Tinidapfen” and fenbendazole was 100% at 21 and 30 days, whereas in group I only 58.3% and 66.6% respectively. In experimental bird groups, hemoglobin concentration was lower by 20.9% compared to control. In the 2nd experimental group, at 3 days after the preparation of the drug, the concentration of hemoglobin was 82.2 ± 0.4 g / l versus 70.8 ± 0.6 g/l, up to 13.9%, while in III In the experimental group, the concentration of hemoglobin increased by only 8.8%. In the 2nd group, an increase in hemoglobin concentration occurred at 14 days by 22.4%, while in the third group of such indicators it was achieved at 21 days. In the II experimental group, an increase in the number of erythrocytes by 15.6% was recorded for 7 days, when similar rates in group ІІ were recorded for 14 days. In the leukogram in the first and second experimental bird groups, eosinophilia was recorded from the beginning of the experiment to 14 days, and by the 21st day the percentage of eosinophils was close to the norm, whereas in the 3rd study group, eosinophilia was recorded up to 21 days, which was 3.9% less, than before the experiment began. In the third experimental group, for 7 days, the percentage of strabismus cancer cells increased by 3.6%, whereas in the second group it was only 1.9% and at 14 days it approached the indicator of the control group. In the 3rd experimental group, control indicators were achieved for 21 days. The percentage of lymphocytes after application of drugs did not change significantly and fluctuated within the range of 51,2 ± 0,2 - 53,9 ± 0,4%. During the 7th day, monocytes increased by 1% in the first study group, by 2,2% in the second group, and by 2,9% in the third group. In the 2nd group of birds, a significant decrease in monocytes was registered at 14 days of the experiment by 8.9%, then in the 3rd experimental group only for 21 days by 15.2%. For spontaneous hemorrhagic hens in all experimental groups of poultry before treatment, the leukocyte index of intoxication was 0.324; 0,351 and 0,355 OD, while in the control during the whole trial, its average rate was 0.273 OD. The leukocyte index of intoxication in the 2nd experimental group on the 7th day of the trial was 0.279, and by 14 days 0.232, while in the third experimental group, with the use of fenbendazole, the index for 7 days was 0.320, for 14 days - 0.280 and for only 21 days - 0.261 OD , which is 22.1% less than the entry level.