Показники обміну холестеролу в організмі свиней за впливу нанохелатів та міцелярної форми токоферолу

Abstract

Наведено нові дані, щодо впливу введення наноаквахелатів біогенних металів (Zn, Fe і Ge) та міцелярної форми токоферолу на показники обміну холестеролу у крові свиней різних вікових груп. Комплексне застосування нанопрепаратів біогенних металів та міцелярної форми токоферолу у меншій мірі впливає на обмін холестеролу у організмі свиней, ніж їх окреме застосування.

Приведены новые данные о влиянии введения наноаквахелатов биогенных металлов (Zn, Fe и Ge) и мицеллярной формы токоферола на показатели обмена холестерина в крови свиней различных возрастных групп. Комплексное применение нанопрепаратов биогенных металлов и мицелярной формы токоферола в меньшей степени влияет на обмен холестерина в организме свиней, чем их отдельное использование.

A new data on the impact of the introduction nanoaquahelat biogenic metals (Zn, Fe and Ge) and micellar form of tocopherol on the exchange rates of cholesterol in the blood of pigs of different ages. The experiment was conducted оп pig farm scientific - practical center "Рода" Podolsky State Agricultural and Technical University in pigs of large white breed under the age of 30-, 60-, 90-, 120-, 150- and 180 days. To eliminate the influence of external factors (season, temperature, pressure, etc.) studies were conducted simultaneously. Pigs was kept under the existing regulations and were free from infectious and parasitic diseases. Experiment conducted according given scheme. Four groups of animals of different ages was fit (10 pigs each). Animals of the first experimental group were injected intramuscularly the complex of microelements nanodrug (Zn, Fe, Ge) in an amount of 2.5 ml. Pigs of the second experimental group were watered vitamin fodder additive in an aqueous micellar solution of vitamin Е at a dose of 2 ml / kg body weight. Animals of the third experimental group were injected intramuscularly with complex of microelements nanodrug (Zn, Fe, Ge) and were watered by micellar form of tocopherol in the doses above. As the material for the research served a blood samples obtained from 5 animals from each group. The plasma samples were tested for total cholesterol (Ch) by enzymatically-photometric method (set CholDAC. Lq company Spectro Med SRL, Moldova), triaglyctrides (TAG) - enzymatically-photometric method (set TG-DAC. Lq), cholesterol high density lipoprotein (CHDL) pretsypitatsio / enzymatically-photometric method (set Chol HDL-DAC. Lq). It was set the increase of total cholesterol in the blood plasma of pigs after weaning until the age of six months, due to the increase of low density lipoprotein in the content, while extremely low density lipoprotein content is somewhat reduced, and the content of high-density lipoprotein only fluctuates within a trend. The content of triacylglycerols in blood plasma of pigs within 6 months of life is reduced on a third. Introduction nano-Zn, Fe and Ge and watering with micellar form of authentic tocopherol promotes the growth of total cholesterol in the blood plasma of animals mainly due to the increase of low density lipoproteins. Complex application of nanobiogenic metals and micellar form of tocopherol has lesser extent affect on the metabolism of cholesterol in the body of pigs than their separate use. Prospects for future research is to study the relationships between physical activity, productivity аnd performance of non-specific resistance of pigs of different ages and developing these indicators correction method using nanomedications.