Терапевтична ефективність прадофлоксацину при уроциститі з урологічним синдромом у кота: клінічний випадок з ветеринарної практики

Abstract

У статті розглянуто питання клінічної ефективності застосування прадофлоксацину у кота, хворого на уроцистит з урологічним синдромом. Застосування прадофлоксацину дозволило покращити клінічний стан тварини та ефективно провести антибіотикотерапію, що свідчить про клінічну ефективність препарату у даному клінічному випадку, яка підтверджується результатами бактеріологічного дослідження сечі після курсу лікування.

The article presents the clinical case of medical treatment of a cat, that is ill with urocystitis that includes urological syndrome, stable recidivating dysuria. They were caused by stable staphylococcus culture that is resistant to the broad-spectrum antibiotics. The cat, which name is Ryzhik, is a metis, the age is 4 years old, the weight is – 4,8 kg, it is neutered, the diet – dry kibble Purina Pro Plan for neutered cats – 70 g per day, boiled water in free access. Past medical history – periodical visits to veterinary clinics with complaints of dysuria, hematuria and loss of appetite; pharmazin-50, ceftriaxone and amoxicillin with clavulanic acid were used in treatment regimen. The course of medical treatment using of these medicines is 10 days at most. The dysuria recurrence is seen after 2-4 months of each course of medical treatment. Before medical treatment the cat had health problems in a way of dysuria, anxiety during urination, macrohematuria; according to results of ultrasonic examination the urinary bladder wall thickening and sediment in this bladder were found. According to results of common urine analysis proteinuria, hematuria and crystalluria were found, the blood level of creatinine was increased to 161,0 mcmol/l (the reference standart – 55,0 – 140,0 mcmol/l). As a result of urine culturing it was set that content of Staphylococcus intermedius to 1,8×104 KFU with marbofloxacin, pradofloxacin, tetracyclines, doxicycline, chloramphenicol sensitivity and nonsensibility to the antibiotics, that were used earlier (ceftriaxone, amoxicillin with clavulanic acid, tylosin). It means the extracted, from the cat’s urine, staphylococcus culture is stable for a define level of resistance to a list of antibiotics. The comprehensive cat’s treatment with using of pradofloxacin has secured the improvement of the animal’s clinical state, namely, it has put aside problems with dysuria, proteinuria , erythrocyturia , removed hyperazotemia, also it has set an effective treatment with antibiotics, that in this case reflects the clinical effectivity of Veraflox drug, which is confirmed by urine culturing results after the medical course.