Патоморфологічна характеристика інтестинальних патологій за генералізованого туберкульозу фазанів

Abstract

Наведені дані патоморфологічного дослідження кишкової стінки фазанів за генералізованого туберкульозу. Діагностовано змішані форми кишкових туберкульозних пошкоджень (вузликово-вузлувато-виразкова, в т.ч., із цикатризацією та стенозом; вузликові – із абсцесоподібними екстра- та інтрамуральними утвореннями) та вузликова їх моноформа.

The results of a pathomorphological study of intestinal wall of pheasants with tuberculosis were discussed. The object of the study were intestines of pheasants (n=5) which died from generalized tuberculosis. The aim of the study was to describe and classify pathological changes in the intestinal wall of pheasants with tuberculosis. Materials and research methods. The work was carried out at the department of normal and pathological morphology of KhSZVA. Methods of postmortem autopsy of birds with partial evisceration, macroscopic analysis of the condition of the intestinal wall, pathological examination of its samples, microscopy according to Zichl-Neelsen for the detection of acid-resistant mycobacteria, PCR were used. Result of the research. We revealed tuberculous lesions with varying degrees of intensity and complexity in the intestinal wall of pheasants. Mycobacterium tuberculosis (stick-shaped red colored microorganisms) detected in smears-prints intestine walls altered fragments using Zichl-Neelsen bacterioscopy. Final diagnosis “Tuberculosis of birds” was established based on macroscopic data, histopathological studies of the intestinal wall, Zichl-Neelsen bacterioscopy, PCR results. Tuberculous granulomas of alternative type predominated in the intestinal wall of pheasants. Proliferative granulomas were rarely detected. The complex of post-tuberculous reparative processes and indicators due to them was classified. In the intestinal wall created alterative type of ulceri with perifocal fibrosis as a result of degradation of tuberculosis granulomas. Scarring of ulcerative areas, local edema, abscess-like wall formations, strictures, partial obstruction of intestines were detected. Mixed forms of tuberculous intestinal lesions: nodular-ulcerative, including, with scarring and stenosis; nodular, including drain, with extra- and intramural abscess-like formations were diagnosed in four pheasants. Nodular monoform of intestinal lesions was classified in one pheasant.