Закономірності морфогенезу селезінки поросят у ранньому постнатальному періоді онтогенезу

Abstract

Селезінка є периферичним органом імунного захисту, де відбуваються проліферація і накопичення лімфоцитів, антитілоутворення і рециркуляція лімфоцитів шляхом міграції через стінки пост капілярних вен та синусоїді червоної пульпи. Досліджено селезінку поросят 1-, 10-, 20-добового віку, із визначенням лінійних промірів органу і відносної площі стромальних та паренхіматозних компонентів і клітинного складу функціональних зон білої пульпи.

A spleen is the peripheral organ of immune defence, where proliferation and accumulation of lymphocytes occur, antibody formation and recirculation of lymphocytes by migration through the walls of the post of capillary veins and sinusoid of red pulp. A spleen of is investigational is the piglets of 1, 10, 20-day age, with determination of linear measurements of an organ and relative area of stromal and parenchymal components and cellular composition of functional zones of white pulp was studied. Qualitative and quantitative indicators of the organ were established on thin paraffinic histocysts stained with hematoxylin and eosin using a light microscope. The relative area was determined by the method of "point counting" using ocular test systems. It was established that in the piglets in the early postnatal period of ontogeny, the structural and functional components of the spleen are formed on the organ and tissue levels of the structural organization. In piglets of 1-day-old age in the spleen, the connective tissue capsule with trabeculae is clearly identified and the parenchyma is divided into red and white pulp. Morphometric indices of spleen of piglets are characterized by a gradual increase in linear measurements and absolute mass. In the spleen, the piglets have the largest relative area of red pulp, against the background of practically identical indices of connective tissue stroma and lymphoid tissue of white pulp. With age, the relative area of the red spleen of the spleen gradually decreases, reaching the minimum values at 20-day age. The white pulp of the spleen in the piglets of the day is clearly divided into periarterial lymphoid vagina and lymph nodes, the relative area of which is minimal. With age, the relative area of white pulp as a whole and its individual components increases, reaching the maximum values of 20-day-old piglets. A significant increase in the relative area of lymphoid tissue was noted at 10-day-old piglets, mainly due to the growth of this indicator of periarterial lymphatic vagina.