Гістологічні зміни у собак за кишкової форми парвовірусного ентериту

Abstract

У статті представлено результати вивчення гістологічних змін у собак за кишкової форми парвовірусного ентериту. За результатами патолого-анатомічного розтину трупів собак, що загинули від кишкової форми парвовірусного ентериту, спостерігаються мікроскопічні зміни в серці, тимусі, печінці, підшлунковій залозі, нирках, легенях, головному мозку та лімфатичних вузлах.

Introduction. On the basis of our analysis of literary sources, the results of monitoring and own research, it was found that viral enteritis occupy a leading place in the infectious pathology of dogs and causes significant damage to animal owners. The most dangerous viral enteritis in the country is parvovirus enteritis. Given the relevance of this issue, the result of our research is to clarify, supplement and generalize the data on the pathomorphology of various organs and tissues of dogs for parvovirus, which will give an opportunity to more precisely determine the effect of the pathogen of the disease on the organism of animals for parvovirus enteritis. The purpose of the work. The purpose of this work was to study and characterize the microscopic changes in the internal organs of dogs contaminated by parvovirus enteritis. Material and methods. The work was carried out at the Faculty of Veterinary Medicine of Zhytomyr National Agroecological University (ZNAEU). Anatomy of the animals was carried out in the special laboratory of the Department of Anatomy and Histology. Results of research and discussion. The article presents the results of the study of histological changes in dogs for the intestinal form of parvovirus enteritis, which were detected using VetExpert and ELISA and PCR express tests. According to the results of the pathologic-anatomical section of the carcasses of dogs which died from the intestinal form of parvovirus enteritis, there are microscopic changes in the internal organs, namely the heart, thymus, kidneys, liver, pancreas, lungs, brain and lymph nodes. Histologic sections were prepared according to commonly accepted techniques. The made histological sections were stained with hematoxylin Caraci and eosin and hematoxylin Borisevich and eosin according to standard prescriptions. Conclusions. Characteristic microscopic changes were detected in the thymus of dilation of blood vessels. Hepatocytes have been enlarged in the state of granular dystrophy. Grain and hydroponic dystrophy are found in the pancreas. In the kidneys serous glomerulitis was found. The lungs were characterized by the expansion and overflow of blood of the parenchyma and stroma venous, venous stasis and edema of the organ. Thus, our complex of pathomorphological changes in dead animals taking into account microscopic research methods can be considered as a characteristic criterion of pathomorphological differential diagnosis of parvovirus enteritis in dogs.