Please use this identifier to cite or link to this item: https://repo.btu.kharkov.ua//handle/123456789/57306
Title: Цистит котів (етіологія, діагностичні критерії, лікувально-профілактичні заходи)
Other Titles: Cystitis of cats (etiology, diagnostic criteria, treatment and prevention measures)
Authors: Лукічова, Яна Василівна
metadata.dc.contributor.advisor: Вікуліна, Г. В.
metadata.dc.contributor.affiliation: Державний біотехнологічний університет, Кафедра внутрішніх хвороб і клінічної діагностики тварин
Keywords: сечовий міхур;цистит;діагностика;коти;bladder;cystitis;diagnosis;cats
Issue Date: 2024
Publisher: Харків: ДБТУ
Citation: Лукічова Я. В. Цистит котів (етіологія, діагностичні критерії, лікувально-профілактичні заходи): кваліфікаційна робота магістра: спец. 211 Ветеринарна медицина; наук. кер. Г. В. Вікуліна. Харків: ДБТУ, 2024. 76 с.
Abstract: Актуальність теми : ураховуючи все більше поширення циститу серед котів, дана тема на зараз є актуальною та затребуваною. Об’єкт дослідження – коти. Предмет дослідження – цистит. Метою даної роботи було визначити ефективність методів діагностики, лікування та профілактики циститу у котів. Для досягнення були визначені наступні завдання: визначити ключові фактори виникнення або схильності котів до циститу, визначити прояв, перебіг та форми прояву циститу, визначення ефективних методів діагностики циститу, визначення діючою схеми лікування та заходів профілактики щодо виникнення захворювання. Теоретичне та практичне значення одержаних результатів. Цінність даної роботи на практиці полягає в аналізі ефективності методів клінічної діагностики, схеми лікування та профілактики циститу серед котів з урахуванням поширеності і зростань кількості клінічних випадків даного захворювання
Relevance of the topic: given the increasing prevalence of cystitis among cats, this topic is currently relevant and in demand. The object of research is cats. The subject of research is cystitis. The purpose of this work was to determine the effectiveness of methods of diagnosis, treatment and prevention of cystitis in cats. The following tasks were defined: to determine the key factors of the occurrence or susceptibility of cats to cystitis; to determine the manifestation, course and forms of manifestation of cystitis; to determination of effective methods of diagnosing cystitis; to determination of the current treatment scheme and preventive measures for the occurrence of the disease. Theoretical and practical significance of the obtained results. The practical value of this work lies in the analysis of the effectiveness of methods of clinical diagnosis, treatment and prevention of cystitis among cats, taking into account the prevalence and increase in the number of clinical cases of this disease.
URI: https://repo.btu.kharkov.ua//handle/123456789/57306
metadata.dcterms.references: 1. Dorsch R, Remer C, Sauter-Louis C, Hartmann K. Feline lower urinary tract disease in a german cat population. A retrospective analysis of demographic data, causes and clinical signs. Tierarztl Prax Ausg K Kleintiere Heimtiere. (2014) 42:231–9. 10.1055/s-0038-1623769 [6]. 2. Piyarungsri K, Tangtrongsup S, Thitaram N, Lekklar P, Kittinuntasilp A. Prevalence and risk factors of feline lower urinary tract disease in Chiang Mai, Thailand. Sci Rep. (2020) 10:196. 10.1038/s41598-019-56968-w [2,3,4,5 ] 3. Reche A, Buffington CAT. Increased tyrosine hydroxylase immunoreactivity in the locus coeruleus of cats with interstitial cystitis. J Urol. (1998) 159:1045–8. 10.1016/S0022-5347(01)63833-3 [16]. 4. Jones BR, Sanson RL, Morris RS. Elucidating the risk factors of feline lower urinary tract disease. New Zeal Vet J. (1997) 45:100. 10.1080/00480169.1997.36003 [15]. 5. pubmed.ncbi.nlm.nih.gov/25351232/ Feline urinary tract pathogens: prevalence of bacterial species and antimicrobial resistance over a 10-year period 6. Roswitha Dorsch 1, Clara von Vopelius-Feldt 1, Georg Wolf 2, Reinhard K Straubinger 2, Katrin Hartmann 1 [7]. 7. Maxie, M. G. (1990). The urinary system in pathology of domestic animals. 4thed. San Diego: Academic Press, San Diego [12]. 8. Buffington CAT. External and internal influences on disease risk in cats. J Am Vet Med Assoc. (2002) 220:994–1002. 10.2460/javma.2002.220.994 [13] . 9. Cameron ME, Casey RA, Bradshaw JWS, Waran NK, Gunn-Moore DA. A study of environmental and behavioural factors that may be associated with feline idiopathic cystitis. J Small Anim Pract. (2004) 45:144–7. 10.1111/j.1748-5827.2004.tb00216.x [14] . 10. Chew DJ. Nonobstructive idiopathic or interstitial cystitis in cats. In: Canine and Feline Nephrology and Urology. (2011). p. 306–40. 10.1016/B978-0-7216-8178-8.10010-7[17 , 18 ,19]. 11. Lulich J, Osborne C, Kruger J. What constitutes a diagnosis of feline idiopathic cystitis? Proceedings of the ACVIM Forum; 2010 June 9–12; Anaheim, California, USA. Colorado, USA, pp 630–631. 12. Patronek GJ, Glickman LT, Beck AM, et al. Risk factors for relinquishment of cats to an animal shelter. J Am Vet Med Assoc 1996; 209: 582–588. 13. Hetrick PF, Davidow EB. Initial treatment factors associated with feline urethral obstruction recurrence rate: 192 cases (2004–2010). J Am Vet Med Assoc 2013; 243: 512–519. 14. Delille M, Frohlich L, Muller RS, et al. Efficacy of intravesical pentosan polysulfate sodium in cats with obstructive feline idiopathic cystitis. J Feline Med Surg 2016; 18: 492–500. 15. Defauw PA, Van de Maele I, Duchateau L, et al. Risk factors and clinical presentation of cats with feline idiopathic cystitis. J Feline Med Surg 2011; 13: 967–975. 16. Dorsch R, Zellner F, Schulz B, et al. Evaluation of meloxicam for the treatment of obstructive feline idiopathic cystitis. J Feline Med Surg 2016; 18: 925–933. 17. Bradley AM, Lappin MR. Intravesical glycosaminoglycans for obstructive feline idiopathic cystitis: a pilot study. J Feline Med Surg 2014; 16: 504–506. 18. Kruger JM, Conway TS, Kaneene JB, et al. Randomized controlled trial of the efficacy of short-term amitriptyline administration for treatment of acute, nonobstructive, idiopathic lower urinary tract disease in cats. J Am Vet Med Assoc 2003; 222: 749–758. 19. Albasan H, Osborne CA, Lulich JP, et al. Rate and frequency of recurrence of uroliths after an initial ammonium urate, calcium oxalate, or struvite urolith in cats. J Am Vet Med Assoc 2009; 235: 1450–1455. 20. Hesse A, Orzekowsky H, Frenk M, et al. Epidemiological data of urinary stones in cats between 1981 and 2008. Tierarztl Prax Ausg K Kleintiere Heimtiere 2012; 40: 95–101. 21. Gerber B, Eichenberger S, Reusch CE. Guarded long-term prognosis in male cats with urethral obstruction. J Feline Med Surg 2008; 10: 16–23. 22. Davidson AP, Ling GV, Stevens F. Urinary tract infection in cats: a retrospective study 1977–1989. California Veterinarian 1992; 46: 32–34. 23. Lulich JP, Osborne CA, Kruger JM. Biologic behavior of feline lower urinary tract diseases. Vet Clin North Am Small Anim Pract 1996; 26: 207–215. 24. Zezza L, Reusch CE, Gerber B. Intravesical application of lidocaine and sodium bicarbonate in the treatment of obstructive idiopathic lower urinary tract disease in cats. J Vet Intern Med 2012; 26: 526–531. 25. Segev G, Livne H, Ranen E, et al. Urethral obstruction in cats: predisposing factors, clinical, clinicopathological characteristics and prognosis. J Feline Med Surg 2011; 13: 101–108. 26. Bovee KC, Reif JS, Maguire TG, et al. Recurrence of feline urethral obstruction. J Am Vet Med Assoc 1979; 174: 93–96. 27. Dorsch R, von Vopelius-Feldt C, Wolf G, et al. Feline urinary tract pathogens: prevalence of bacterial species and antimicrobial resistance over a 10-year period. Vet Rec 2015; 176: 201. 28. Bailiff NL, Nelson RW, Feldman EC, et al. Frequency and risk factors for urinary tract infection in cats with diabetes mellitus. J Vet Intern Med 2006; 20: 850–855. 29. Dorsch R, von Vopelius-Feldt C, Wolf G, et al. Urinary tract infections in cats. Prevalence of comorbidities and bacterial species, and determination of antimicrobial susceptibility to commonly used antimicrobial agents. Tierarztl Prax Ausg K Kleintiere Heimtiere 2016; 44: 227–236. 30. Mayer-Roenne B, Goldstein RE, Erb HN. Urinary tract infections in cats with hyperthyroidism, diabetes mellitus and chronic kidney disease. J Feline Med Surg 2007; 9: 124–132. 31. White JD, Stevenson M, Malik R, et al. Urinary tract infections in cats with chronic kidney disease. J Feline Med Surg 2013; 15: 459–465. 32. Hugonnard M, Chalvet-Monfray K, Dernis J, et al. Occurrence of bacteriuria in 18 catheterised cats with obstructive lower urinary tract disease: a pilot study. J Feline Med Surg 2013; 15: 843–848. 33. Bass M, Howard J, Gerber B, et al. Retrospective study of indications for and outcome of perineal urethrostomy in cats. J Small Anim Pract 2005; 46: 227–231. 34. Gunn-Moore DA, Shenoy CM. Oral glucosamine and the management of feline idiopathic cystitis. J Feline Med Surg 2004; 6: 219–225. 35. Lekcharoensuk C, Lulich JP, Osborne CA, et al. Association between patient-related factors and risk of calcium oxalate and magnesium ammonium phosphate urolithiasis in cats. J Am Vet Med Assoc 2000; 217: 520–525. 36. Cameron ME, Casey RA, Bradshaw JW, et al. A study of environmental and behavioural factors that may be associated with feline idiopathic cystitis. J Small Anim Pract 2004; 45: 144–147. 37. Osborne CA, Lulich JP, Thumchai R, et al. Feline urolithiasis. Etiology and pathophysiology. Vet Clin North Am Small Anim Pract 1996; 26: 217–232. 38. Lund HS, Eggertsdottir AV. Recurrent episodes of feline lower urinary tract disease with different causes: possible clinical implications. J Feline Med Surg 2019; 21: 590–594. 39. Markwell P, Buffington C, Chew D, et al. Clinical evaluation of commercially available urinary acidification diets in the management of idiopathic cystitis in cats. J Am Vet Med Assoc 1999; 214: 361–365. 40. Westropp JL, Lulich J. Medical management of urolithiasis. In: Elliott J, Grauer GF, Westropp J. (eds). BSAVA manual of canine and feline nephrology and urology. Quedgely: BSAVA, 2017, pp 304–310. 41. Buffington CA, Westropp JL, Chew DJ, et al. Clinical evaluation of multimodal environmental modification (MEMO) in the management of cats with idiopathic cystitis. J Feline Med Surg 2006; 8: 261–268. 42. Lee JA, Drobatz KJ. Characterization of the clinical characteristics, electrolytes, acid–base, and renal parameters in male cats with urethral obstruction. J Vet Emerg Crit Care 2003; 13: 227–233. 43. Larson J, Kruger JM, Wise AG, Kaneene JB, Miller R, Fitzgerald SD, et al.. Nested case-control study of feline calicivirus viruria, oral carriage, and serum neutralizing antibodies in cats with idiopathic cystitis. J Vet Intern Med. (2011) 25:199–205. 10.1111/j.1939-1676.2011.0685.x 44. Kruger JM, Venta PJ, Swenson CL, Syring R, Gibbons-Burgener SN, Richter M, et al.. Prevalence of bovine herpesvirus-4 infection in cats in central Michigan. J Vet Intern Med. (2000) 14:593–7. 10.1111/j.1939-1676.2000.tb02282.x 45. Rice CC, Kruger JM, Venta PJ, Vilnis A, Maas KA, Dulin JA, et al.. Genetic characterization of 2 novel feline caliciviruses isolated from cats with idiopathic lower urinary tract disease. J Vet Intern Med. (2002) 16:293–302. 10.1111/j.1939-1676.2002.tb02372.x 46. Makino A, Shimojima M, Miyazawa T, Kato K, Tohya Y, Akashi H. Junctional adhesion molecule 1 is a functional receptor for feline calicivirus. J Virol. (2006) 80:4482–90. 10.1128/JVI.80.9.4482-4490.2006 47. Stuart AD, Brown TDK. Alpha 2,6-linked sialic acid acts as a receptor for feline calicivirus. J Gen Virol. (2007) 88:177–86. 10.1099/vir.0.82158-0 48. Lewis SA. Everything you wanted to know about the bladder epithelium but were afraid to ask. Am J Physiol Renal Physiol. (2000) 278:F867–74. 10.1152/ajprenal.2000.278.6.F867 49. Hauser PJ, VanGordon SB, Seavey J, Sofinowski TM, Ramadan M, Abdullah S, et al.. Abnormalities in expression of structural, barrier and differentiation related proteins, and chondroitin sulfate in feline and human interstitial cystitis. J Urol. (2015) 194:571–7. 10.1016/j.juro.2015.01.090 50. Buffington CAT, Blaisdell JL, Binns SP, Woodworth BE. Decreased urine glycosaminoglycan excretion in cats with interstitial cystitis. J Urol. (1996) 155:1801–4. 10.1016/S0022-5347(01)66201-3 51. Pereira DA, Aguiar JAK, Hagiwara MK, Michelacci YM. Changes in cat urinary glycosaminoglycans with age and in feline urologic syndrome. BBA Gen Subj. (2004) 1672:1–11. 10.1016/j.bbagen.2004.02.002 52. Lavelle JP, Meyers SA, Ruiz WG, Buffington CAT, Zeidel ML, Apodaca G. Urothelial pathophysiological changes in feline interstitial cystitis: a human model. Am J Physiol Renal. (2000) 278:F540–3. 10.1152/ajprenal.2000.278.4.F540 53. Lemberger SIK, Deeg CA, Hauck SM, Amann B, Hirmer S, Hartmann K, et al.. Comparison of urine protein profiles in cats without urinary tract disease and cats with idiopathic cystitis, bacterial urinary tract infection, or urolithiasis. Am J Vet Res. (2011) 72:1407–15. 10.2460/ajvr.72.10.1407 54. Lemberger SIK, Dorsch R, Hauck SM, Amann B, Hirmer S, Hartmann K, et al.. Decrease of trefoil factor 2 in cats with feline idiopathic cystitis. BJU Int. (2011) 107:670–7. 10.1111/j.1464-410X.2010.09500.x 55. Miller AH, Maletic V, Raison CL. Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression. Biol Psychiat. (2009) 65:732–41. 10.1016/j.biopsych.2008.11.029 56. Strouse TB. The relationship between cytokines and pain/depression: a review and current status. Curr Pain Headache Rep. (2007) 11:98–103. 10.1007/s11916-007-0005-y 57. Raison CL, Miller AH. When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders. Am J Psychiat. (2003) 160:1554–65. 10.1176/appi.ajp.160.9.1554 58. Korte SM, Koolhaas JM, Wingfield JC, McEwen BS. The Darwinian concept of stress: benefits of allostasis and costs of allostatic load and the trade offs in health and disease. Neurosci Biobehav R. (2005) 29:3–38. 10.1016/j.neubiorev.2004.08.009 59. Buffington CAT. Visceral pain in humans: lessons from animals. Curr Pain Headache Rep. (2001) 5:44–51. 10.1007/s11916-001-0009-y 60. Reche A, Buffington CAT. Increased tyrosine hydroxylase immunoreactivity in the locus coeruleus of cats with interstitial cystitis. J Urol. (1998) 159:1045–8. 10.1016/S0022-5347(01)63833-3 61. Westropp JL, Welk KA, Buffington CA. Small adrenal glands in cats with feline interstitial cystitis. J Urol. (2003) 170(6 Pt 1):2494–7. 10.1097/01.ju.0000095566.63870.66 62. Valentino RJ, Miselis RR, Pavcovich LA. Pontine regulation of pelvic viscera: pharmacological target for pelvic visceral dysfunctions. Trends Pharmacol Sci. (1999) 20:253–60. 10.1016/S0165-6147(99)01332-2 63. Buffington CAT. Comorbidity of interstitial cystitis with other unexplained clinical conditions. J Urol. (2004) 172(4 Pt 1):1242–8. 10.1097/01.ju.0000137953.49304.6c
Appears in Collections:211 - "Ветеринарна медицина" (Магістри)

Files in This Item:
File Description SizeFormat 
2024_M_211_18_05_Lukichova_YA_V.pdf
  Restricted Access
1.82 MBAdobe PDFView/Open Request a copy


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.